Applications
Skin rejuvenation, used with ZFace.- Skin texture, skin barrier strength and overall skin quality, the areas Zimmer names Exo-Z's intensive dermal treatment as supporting.
- Irritated, sensitive, stressed and problematic skin, addressed by Exo-Z's named Centella Callus Extract ingredient.
- Deep hydration and intensive nourishment, addressed by Exo-Z's named Truffle Extract ingredient.
- Collagen stimulation, firmness and elasticity, an anti-aging and skin-firming use addressed by Exo-Z's named Peptide Complex ingredient.
How it works
Exo-Z is formulated with high-purity phyto exosomes, combined with a peptide complex, multi-vitamins, amino acids and antioxidants. Zimmer describes these nano-sized, plant-derived exosomes as natural delivery systems that transport the active ingredients into the skin, and states that the cell-to-cell communication they carry influences tissue repair, inflammation regulation, immune response and cellular renewal.
Exosomes per vial
8.8 billion phyto exosomes, in freeze-dried (lyophilized) form
Activating solution
High and low molecular weight hyaluronic acid, an amino acid complex, a vitamin B complex and glutathione
First session
25 minutes, within Zimmer's protocol combining Exo-Z with ZFace and ZHydro; Zimmer states noticeable improvements can be seen after this first session
Preparation
Prepared immediately before application, which Zimmer states ensures stability and effectiveness, a sterile and safe application, and reliable storage in professional settings
Visible result
Smoother, more hydrated, more even and visibly regenerated skin after one session, within the same ZFace and ZHydro protocol
Why this product
Dual-chamber, freeze-dried
Exo-Z combines exosomes with peptides, vitamins and amino acids in a dual-chamber freeze-dried ampoule.
Plant-derived, by Zimmer's own wording
"Exclusively plant-derived exosomes provide maximum purity and safety, eliminating risks associated with animal-based sources."
No human donor material anywhere in this portfolio
DNA Nexus confirmed on 17 August 2026 that every regenerative product it carries, Exo-Z included, is either autologous or plant-derived or synthetic. There is no human allogeneic material in the range.
Bundled at the start
Every ZFace ships with 8 Exo-Z ampoules, so a clinic treats its first patients before placing a reorder.
What to know
Practice value
Exo-Z is a per-treatment consumable, ordered on its own schedule once a clinic works through the ampoules bundled with its ZFace.
Its plant-derived sourcing sits alongside the same fact across the rest of DNA Nexus's regenerative catalogue: no product in the portfolio uses human donor material.
What is Exo-Z?
A dual-chamber, freeze-dried exosome ampoule with peptides, vitamins and amino acids, used with ZFace.
Where do the exosomes in Exo-Z come from?
Zimmer states they are exclusively plant-derived, which the manufacturer positions against the risks of animal-based sources.
Does Exo-Z come with ZFace?
Yes, 8 ampoules ship with every ZFace as part of its starter kit.
What are exosomes, in Zimmer's own explanation?
Zimmer describes exosomes as nano-sized extracellular vesicles that cells release naturally, acting as messengers that carry proteins, lipids and genetic material, such as mRNA and microRNA, between cells. Zimmer notes that exosomes were once considered cellular waste before this role was recognized, and are now used in regenerative medicine and skincare.
DNA Nexus support
DNA Nexus will handle Exo-Z reorders alongside the rest of the Zimmer consumables line. After-sales contact runs from Cairo, alongside the rest of the DNA Nexus Zimmer portfolio.
Exo-Z - Zimmer